Plant and Microbe Molecular Interactions----INSTITUTE OF MICROBOLOGY CHINESE ACADEMY OF SCIENCES

Principal Investigator：LIU Jun, Ph.D., Professor

State Key Laboratory of Plant Genomics

Telephone/Fax：+86 (0) 10-64806131
E-mail：Junliu@im.ac.cn
Add.:NO.1 West Beichen Road, Chaoyang District, Beijing 100101, China

Research interests
Research in the Liu laboratory primarily focuses on the molecular mechanisms of plant innate immunity upon pathogen invasion. We are interested in elucidating each component function of the host immune signaling complexes and attempt to understand how plants utilize the immune complexes to fight against pathogen colonization. The Arabidopsis-Pseudomonas syringae model system is currently employed in the laboratory to investigate the plant and microbe interaction at molecular level. Recently, we also initiated a project to characterize the functions of secreting proteins from rice blast fungus (Magnaporthe oryzae).

Background

1999-2004 Ph.D, Nanjing Agricultural University，China
2004-2007 Postdoctoral researcher, Institute of genetics and developmental biology, Chinese Academy of Sciences，China
2007-2013 Postdoctoral researcher /Assistant Project scientist, University of California, Davis, USA
2012-present Principal Investigator through “Hundred Talents Program” of China

Membership/Activity in professional society

2009-present International Society for Molecular Plant-Microbe Interactions member
2021-present Senior Editor of Molecular Plant Pathology

Area of Specialization

Molecular biology, genetics and proteomics of plant-microbe interactions

Selected publications  and Books（* corresponding author）

1. Yingying Xing^#, Ning Xu^#, Deepak D. Bhandari, Dmitry Lapin, Xinhua Sun, Xuming Luo, Yeqiong Wang, Jidong Cao, Hongbin Wang, Gitta Coaker, Jane E. Parker, and Jun Liu*. Bacterial effector targeting of a plant iron sensor facilitates iron acquisition and pathogen colonization. The Plant Cell (2021, accepted)

2. Ning Xu^#, Xuming Luo^#, Wei Wu^#, Yingying Xing, Yinbo Liang, Yanzhi Liu, Huasong Zou, Hailei Wei, and Jun Liu*. A plant lectin receptor-like kinase phosphorylates the bacterial effector AvrPtoB to dampen its virulence in Arabidopsis. Molecular Plant, 2020, 13:1499–1512

3. Fanwei Meng^#, Chao Yang^#, Jidong Cao, Huan Chen, Jinhuan Pang, Qiqi Zhao, Zongyi Wang, Zheng Qing Fu, and Jun Liu*. A bHLH transcription activator regulates defense signaling by nucleo-cytosolic trafficking in rice. Journal of Integrative Plant Biology, 2020, DOI:10.1111/jipb.12922

4. Md Azizul Islam, Jin-huan Pang, Fan-wei Meng, Ya-wen Li, Ning Xu, Chao Yang*, and Jun Liu*. Putrescine, spermidine, and spermine play distinct roles in rice salt tolerance. Journal of Integrative Agriculture, 2020, 19(3): 643–655

5. Xuming Luo^#, Wei Wu^#, Yingbo Liang#, Ning Xu, Zongyi Wang, Huasong Zou, and Jun Liu*. Tyrosine phosphorylation of the lectin receptor-like kinase LORE regulates plant immunity. The EMBO Journal, 2020, e102856

6. Chao Yang^#, Yongqi Yu^#, Junkai Huang, Fanwei Meng, Jinhuan Pang, Qiqi Zhao, Aziz Islam, Ning Xu, Yun Tian, and Jun Liu*. Binding of the Magnaporthe oryzae chitinase MoChia1 by a rice tetratricopeptide repeat protein allows free chitin to trigger immune responses. The Plant Cell, 2019, 31: 172–188

7. Zhang M, Chiang Y , Toru？o T, Lee D , Ma M , Liang X, Lal N , Lemos M , Lu Y, Ma S , Liu J, Day B , Dinesh-Kumar S, Dehesh K, Dou D, Zhou J, Coaker G. The MAP4 Kinase SIK1 Ensures Robust Extracellular ROS Burst and Antibacterial Immunity in Plants. Cell Host Microbe, 2018, 24 (3):379-391

8. Xuming Luo^#, Jidong Cao^#, Junkai Huang^#, Zongyi Wang, Zhengyan Guo, Yihua Chen, Shumei Ma*, and Jun Liu*. Genome sequencing and comparative genomics reveal the potential pathogenic mechanism of Cercospora sojina Hara on soybean. DNA Research, 2018,25(1)：25-37

9. Xuming Luo^#, Ning Xu^#, Junkai Huang, Feng Gao, Huasong Zou, Marie Boudsocq, Gitta Laurel Coaker, and Jun Liu*. A Lectin Receptor-like Kinase mediates pattern-triggered salicylic acid signaling. Plant Physiology, 2017, 174(4):2501-2514

10. Jidong Cao^#, Yongqi Yu^#, Yan chen, Suiyan Li*, and Jun Liu*. Genome re-sequencing analysis uncovers pathogenecity-related genes undergoing positive selection in Magnaporthe oryzae. SCIENCE CHINA Life Sciences. 2017, 60(8):880-890

11. Ning Xu, Xuming Luo, Wen Li, Zongyi Wang, and Jun Liu*. The bacterial effector AvrB-induced RIN4 hyperphosphorylation is mediated by receptor-like cytoplasmic kinase complex in Arabidopsis. Molecular Plant Microbe Interaction, 2017, 30(6):502-512

12. Yang C, Li W, Cao J, Meng F, Yu Y, Huang J, Jiang L, Liu M, Zhang Z, Chen X, Miyamoto K, Yamane H, Zhang J, Chen S, Liu J*. Activation of ethylene signaling pathways enhances disease resistance by regulating ROS and phytoalexin production in rice. The Plant Journal, 2017, 89(2):338-353

13. Jidong Cao, Chao Yang, Lingjuan Li, Lan Jiang, Chuanwan Wu, Qingyun bu, Guixian Xia, Xiaoyun Liu, Yuanming Luo*, and Jun Liu*. Rice plasma membrane proteomics reveals Magnaporthe oryzae promotes susceptibility by sequential activation of host hormone signaling pathways. Molecular Plant Microbe Interaction, 2016, 29(11):902-913

14. Henry E, Fung N, Liu J, Drakakaki G, Coaker G*. Beyond glycolysis: GAPDHs are multi-functional enzymes involved in regulation of ROS, autophagy, and plant immune responses. PLoS Genet, 2015 Apr 28;11(4):e1005199

15. Hurley B, Lee D, Mott A, Wilton M, Liu J, Liu YC, Angers S, Coaker G, Guttman DS, Desveaux D*. The Pseudomonas syringae type III effector HopF2 suppresses Arabidopsis stomatal immunity. PLoS One, 2014 Dec 11;9(12):e114921

16. Jun Liu, James Elmore, Daniel Lin and Gitta Coaker*. A receptor like cytoplasmic protein kinase phosphorylates RIN4, triggerring plant innate immunity. Cell Host &Microbe, 2011,9, 137–146

17. Tao Chen#, Jun Liu#, Gang Lei, Yun-Feng Liu, Zhi-Gang Li, Jian-Jun Tao, Yu-Jun Hao, Yang-Rong Cao, Qing Lin, Wan-Ke Zhang, Biao Ma, Shou-Yi Chen*, and Jin-Song Zhang*. Effects of Tobacco Ethylene Receptor Mutations on Receptor Kinase Activity, Plant Growth and Stress Responses. Plant and Cell Physiology.2009 50(9):1636-1650 (*: equal contribution)

18. Jun Liu, James Elmore, Anja Fuglsang, Michael Palmgren. Brian Staskawicz and Gitta Coaker*. RIN4 Functions with Plasma Membrane H+-ATPases to Regulate Stomatal Apertures during Pathogen Attack. PLoS Biology. 2009, 7(6): e1000139.