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Faculty and Staff
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Genomic Resources Mining Research Group



Principle Investigator:
Dr. Prof.Songnian Hu







Research area


Genome mining; Bioinformatics research



Research Interest


Development of metagenomic technologies and methods for analyzing microbial communities.

  • Single-cell metagenomic detection and library construction technology for precision sampling in microbial resource.
  • Precision medicine analysis toolkit for better understanding of the correlation between metabolism network, colony evolution and the clinical phenotypes.

Construction of comprehensive bioinformatic platform for microbial multi-omics data.

  • Microbial genomics comprehensive analysis platform for multi-source omics data from human, animals and plants.
  • Tracking database for metadata of samples and workflows, which enables long-term tracking and multidimensional comparison.

Bioinformatic datamining and utilizing of microbial genome resources.

  • Discovery of important genes and functional elements from microbial genome resources.
  • Identification and characterization of new functions of genes and elements, analysis of the evolution and genetics of these elements.
  • Supply of genomic knowledgebase for synthetic biology, genome editing and genome engineering.


Group members


Principle investigator

Dr. Prof. Songnian Hu

Institute of Microbiology, Chinese Academy of Sciences, No.1 West Beichen Road, Chaoyang District, Beijing 100101, P. R. China

Tel/ Fax: 86-10-64806939



Jul. 1991:   B.S. in Food Engineering, Tianjin University of Commerce, Tianjin, China
Jul. 1996:   Ph.D. in Plant Biochemistry, China Agricultural University, Beijing, China 


Professional Experience


1996-1999: Assistant Professor, Institute of Basic Medical Sciences, CAMS, China

1998-1999: Senior Fellow, Genome Center, University of Washington, USA.

1999-2002: Chief Engineer, Beijing Genomics Institute, China

2002-2004: Director, Hangzhou Genomics Institute, China

2004-2019: Professor for Beijing Institute of Genomics, CAS, China

2006-2019: Deputy Director for CAS Key Laboratory of Genome Sciences and Information, CAS, China

Since 2019: Professor for Institute of Microbiology, CAS, China



Permanent stuff


Dr. Yingfeng Luo
Associate Professor
Research Interest:
Bioinformatics, comparative genomic analysis and its applications

Xinyu Tan
Laboratory Technician
Research Interest:
Senior laboratory technician

Dr. Jianing Geng
Assistant professor
Research Interest:
Microbial Functional

Chang Shu
Assistant professor
Research Interest:

Ruoyu Jia
Research assistant

Xiaochun Bi
Laboratory technician
Research Interest:
Responsible for experimental operation


Postdoctoral fellow


Senghan Gao
Postdoctoral fellow
Research Interests:
Precision structual analysis of microbial genomes and Development of bioinformatics tools and databases


Graduate students


Hao Liang (Ph. D student)

Yan Sun (Ph. D student)

Qian-hui Zhu (Ph. D student)

Tao Yu (Ph. D student)

Xin Zheng (M. Sc student)

Sai-nan Luo (M. Sc student)

Ke-xin Li (M. Sc student)

Jing-yi Nie (M. Sc student)



Representative Pictures


The genome assembly and genetic analysis of maize cultivar HuangZaoSi (2019)


Geographic distribution of maize planting area and yield in major

maize-growing countries. Pie charts (red) show the proportions of planted areas

of HZS-related cultivars within each province of China.


New improvements and updates for web base phylogenetic tree visualization and annotation toolkit EvolView. (2019)




Research of genome structural plasticity -Rice






Research of genome structural plasticity –The rubber tree



Research of genome structural plasticity –Date palm






Research of genome structural plasticity –Genomics of microbiology





Microbiology and diseases



EvolView v1/v2/v3



Recent Publications


1. Li, C., Song, W., Luo, Y., Gao, S., Zhang, R., Shi, Z., Wang, X., Wang, R., Wang, F., Wang, J., Zhao, Y., Su, A., Wang, S., Li, X., Luo, M., Wang, S., Zhang, Y., Ge, J., Tan, X., Yuan, Y., Bi, X., He, H., Yan, J., Wang, Y., Hu, S*. & Zhao, J. The HuangZaoSi maize genome provides insights into genomic variation and improvement history of maize. Molecular Plant12, 402-409, doi:10.1016/j.molp.2019.02.009 (2019).

2. Subramanian, B., S. Gao, M. J. Lercher, S. Hu* and W. H. Chen*, Evolview v3: a webserver for visualization, annotation, and management of phylogenetic trees. Nucleic Acids Res, 2019. 47(W1): p. W270-W275.

3. Tang, C*., M. Yang, Y. Fang, Y. Luo, S. Gao, X. Xiao, Z. An, B. Zhou, B. Zhang, X. Tan, H. Y. Yeang, Y. Qin, J. Yang, Q. Lin, H. Mei, P. Montoro, X. Long, J. Qi, Y. Hua, Z. He, M. Sun, W. Li, X. Zeng, H. Cheng, Y. Liu, J. Yang, W. Tian, N. Zhuang, R. Zeng, D. Li, P. He, Z. Li, Z. Zou, S. Li, C. Li, J. Wang, D. Wei, C. Q. Lai, W. Luo, J. Yu, S. Hu* and H. Huang*, The rubber tree genome reveals new insights into rubber production and species adaptation. Nat Plants, 2016. 2(6): p. 16073.

4. Wang, S., Wang, S., Luo, Y., Xiao, L., Luo, X., Gao, S., Dou, Y., Zhang, H., Guo, A., Meng, Q., Hou, J., Zhang, B., Zhang, S., Yang, M., Meng, X., Mei, H., Li, H., He, Z., Zhu, X., Tan, X., Zhu, X.-Q., Yu, J., Cai, J., Zhu, G., Hu, S*. & Cai, X. Comparative genomics reveals adaptive evolution of Asian tapeworm in switching to a new intermediate host. Nature communications7, 12845, doi:10.1038/ncomms12845 (2016).

5. He, Z., H. Zhang, S. Gao, M. J. Lercher, W. H. Chen* and S. Hu*, Evolview v2: an online visualization and management tool for customized and annotated phylogenetic trees. Nucleic Acids Res, 2016. 44(W1): p. W236-41.

6. Dai, X., Y. Tian, J. Li, Y. Luo, D. Liu, H. Zheng, J. Wang, Z. Dong, S. Hu* and L. Huang*,Metatranscriptomic analyses of plant cell wall polysaccharide degradation by microorganisms in the cow rumen. Appl Environ Microbiol, 2015. 81(4): p. 1375-86.





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Institute Of Microbiology Chinese Academy of Sciences
NO.1 West Beichen Road, Chaoyang District, Beijing 100101, China Phone: 0086-10-64807462 Fax: 0086-10-64807468 Email: office@im.ac.cn