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The lab of genomic resources mining

 

      

 

Principal Investigator: Dr. Prof.Songnian Hu

 

Telephone/Fax:010-84097458

E-mail:husn@im.ac.cn

Add.:NO.1 West Beichen Road, Chaoyang District, Beijing 100101, China

Research area

Genome mining; Bioinformatics research

Research interests 

1)     Development of metagenomic technologies and methods for analyzing microbial communities.

a)   Single-cell metagenomic detection and library construction technology for precision sampling in microbial resource.

b)   Precision medicine analysis toolkit for better understanding of the correlation between metabolism network, colony evolution and the clinical phenotypes. 

2)   Construction of comprehensive bioinformatics platform for microbial multi-omics data.

a)   Microbial genomics comprehensive analysis platform for multi-source omics data from human, animals and plants.

b)   Tracking database for metadata of samples and workflows, which enables long-term tracking and multidimensional comparison.

 

3)   Bioinformatic datamining and utilization of microbial genome resources.

a)   Discovery of important genes and functional elements from microbial genome resources.

b)   Identification and characterization of new functions of genes and elements, analysis of the evolution and genetics of these elements.

c)   Supply of genomic knowledgebase for synthetic biology, genome editing and genome engineering.

 

Group Members

 

 

Principle investigator

Dr. Prof. Songnian Hu 

Institute of Microbiology, Chinese Academy of Sciences, No.1 West Beichen Road, Chaoyang District, Beijing 100101, P. R. China

Tel/ Fax: 86-10-84097458
E-mail: 
husn@im.ac.cn

 

Education 

Jul. 1991:   B.S. in Food Engineering, Tianjin University of Commerce, Tianjin, China

Jul. 1996:   Ph.D. in Plant Biochemistry, China Agricultural University, Beijing, China 

Professional Experience

1996-1999: Assistant Professor, Institute of Basic Medical Sciences, CAMS, China

1998-1999: Senior Fellow, Genome Center, University of Washington, USA.

1999-2002: Chief Engineer, Beijing Genomics Institute, China

2002-2004: Director, Hangzhou Genomics Institute, China

2004-2019: Professor for Beijing Institute of Genomics, CAS, China

2006-2019: Deputy Director for CAS Key Laboratory of Genome Sciences and Information, CAS, China

Since 2019: Professor for Institute of Microbiology, CAS, China

Permanent stuff

 

Dr. Yingfeng Luo
Associate Professor
luoyf@im.ac.cn
Research Interest:
Bioinformatics, comparative genomic analysis and its applications

Xinyu Tan
Laboratory Technician
tanxy@im.ac.cn
Research Interest:
Senior laboratory technician

Dr. Jianing Geng
Assistant professor
gengjn@im.ac.cn
Research Interest:
Microbial Functional
Genomics,Bioinformatics&&Biomedicine

Chang Shu
Assistant professor
shuc@im.ac.cn
Research Interest:
Pharmacogenomics
Oncogenomics,DiseaseGenomics

Ruoyu Jia
Research assistant
jiary@im.ac.cn

Xiaochun Bi
Laboratory technician
bixc@im.ac.cn
Research Interest:
Responsible for experimental operation

Postdoctoral fellow

 

Gao shenghan
Postdoctoral fellow
gaoshh@im.ac.cn
Research Interests:
Precision structual analysis of microbial genomes and Development of bioinformatics tools and databases

Graduate students

 

 

Liang Hao

Ph. D student

SunYan
Ph. D student

Qianhui Zhu
Ph. D student

Tao Yu
Ph. D student

Xin Zheng
M. Sc student

Sainan Luo
M. Sc student

Kexin Li
M. Sc student

Jingyi Nie
M. Sc student

Representative Pictures

 

Research of genome structural plasticity -Rice

 

Research of genome structural plasticity –The rubber tree

 

Research of genome structural plasticity –Date palm

 

 

Research of genome structural plasticity –Genomics of microbiology

 

 

 

Microbiology and diseases

  

 EvolView v1/v2/v3 

Recent Publications

 

1. Li, C., Song, W., Luo, Y., Gao, S., Zhang, R., Shi, Z., Wang, X., Wang, R., Wang, F., Wang, J., Zhao, Y., Su, A., Wang, S., Li, X., Luo, M., Wang, S., Zhang, Y., Ge, J., Tan, X., Yuan, Y., Bi, X., He, H., Yan, J., Wang, Y., Hu, S*. & Zhao, J. The HuangZaoSi maize genome provides insights into genomic variation and improvement history of maize. Molecular Plant12, 402-409, doi:10.1016/j.molp.2019.02.009 (2019).

2. Subramanian, B., S. Gao, M. J. Lercher, S. Hu* and W. H. Chen*, Evolview v3: a webserver for visualization, annotation, and management of phylogenetic trees. Nucleic Acids Res, 2019. 47(W1): p. W270-W275.

3. Tang, C*., M. Yang, Y. Fang, Y. Luo, S. Gao, X. Xiao, Z. An, B. Zhou, B. Zhang, X. Tan, H. Y. Yeang, Y. Qin, J. Yang, Q. Lin, H. Mei, P. Montoro, X. Long, J. Qi, Y. Hua, Z. He, M. Sun, W. Li, X. Zeng, H. Cheng, Y. Liu, J. Yang, W. Tian, N. Zhuang, R. Zeng, D. Li, P. He, Z. Li, Z. Zou, S. Li, C. Li, J. Wang, D. Wei, C. Q. Lai, W. Luo, J. Yu, S. Hu* and H. Huang*, The rubber tree genome reveals new insights into rubber production and species adaptation. Nat Plants, 2016. 2(6): p. 16073.

4. Wang, S., Wang, S., Luo, Y., Xiao, L., Luo, X., Gao, S., Dou, Y., Zhang, H., Guo, A., Meng, Q., Hou, J., Zhang, B., Zhang, S., Yang, M., Meng, X., Mei, H., Li, H., He, Z., Zhu, X., Tan, X., Zhu, X.-Q., Yu, J., Cai, J., Zhu, G., Hu, S*. & Cai, X. Comparative genomics reveals adaptive evolution of Asian tapeworm in switching to a new intermediate host. Nature communications7, 12845, doi:10.1038/ncomms12845 (2016).

5. He, Z., H. Zhang, S. Gao, M. J. Lercher, W. H. Chen* and S. Hu*, Evolview v2: an online visualization and management tool for customized and annotated phylogenetic trees. Nucleic Acids Res, 2016. 44(W1): p. W236-41.

6. Dai, X., Y. Tian, J. Li, Y. Luo, D. Liu, H. Zheng, J. Wang, Z. Dong, S. Hu* and L. Huang*,Metatranscriptomic analyses of plant cell wall polysaccharide degradation by microorganisms in the cow rumen. Appl Environ Microbiol, 2015. 81(4): p. 1375-86.

 

 

 

 

 
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Institute Of Microbiology Chinese Academy of Sciences
NO.1 West Beichen Road, Chaoyang District, Beijing 100101, China Phone: 0086-10-64807462 Fax: 0086-10-64807468 Email: office@im.ac.cn