Molecular genetics and resource exploitation of lactic acid  bacteria

1996-1999
Lecturer, School of Light Industry, Anhui Agricultural University
2003-2008
Assistant Professor, Institute of Microbiology, Chinese Academy of Sciences
2008-2011
Associate Professor, Institute of Microbiology, Chinese Academy of Sciences
2014-2019
Vice Director (On Secondment), Institute of Microbiology, Jiangxi Academy of Sciences
2011-Present
Professor, Institute of Microbiology, Chinese Academy of Sciences

1. Xia T, Wang T*, Zhang J, Li H, Sun J, Liu S, Yun F, Teng K, Jin S, Wang S, Fu Z, Zhong J*. In-depth proteomic analysis of alfalfa silage inoculated with Lactiplantibacillus plantarum reveals protein transformation mechanisms and optimizes dietary nitrogen utilization. International Journal of Biological Macromolecules. 2025 Apr 3;309(Pt 2):142638.
2.  Tahir M, Wang T, Zhang J, Xia T, Deng X, Cao X, Zhong J*. Compound lactic acid bacteria enhance the aerobic stability of Sesbania cannabina and corn mixed silage. BMC Microbiology. 2025 Feb 7;25(1):68.
3. Xia T, Huang F, Yun F, Liu Y, Wang T, Wang S, Jin S, Ma X, Wang W, He J, Teng K*, Zhong J*. Lacticaseibacillus rhamnosus LRJ-1 alleviates constipation through promoting gut Bacteroides-derived γ-aminobutyric acid production. Current Research in Food Science. 2024 Nov 12 (9) 100924
4. Xia T, Tahir M, Wang T*, Wang Y, Zhang X, Liu S, Teng K, Fu Z, Yun F, Wang S，Jin S, Hu J, Zhong J*. Lactobacillus cocktail and cellulase synergistically improve the fiber transformation rate in Sesbania cannabina and sweet sorghum mixed silage. Chemical and Biological Technologies in Agriculture 2024 Jun 11:81
5. Xia T, Teng K*, Liu Y, Guo Y, Huang F, Tahir M, Wang T, Zhong J*. A novel two-component bacteriocin, acidicin P, and its key residues for inhibiting Listeria monocytogenes by targeting the cell membrane. Microbiology Spectrum 2023 Jun 8; e0521022.
6. Li L, Zhang J*, Zhou L, Shi H, Mai H, Su J, Ma X, Zhong J*. The first lanthipeptide from Lactobacillus iners, inecin L, exerts high antimicrobial activity against human vaginal pathogens. Applied and Environmental Microbiology 2023 Mar 29;89(3):e0212322.
7. Teng K, Huang F, Liu Y, Wang Y, Xia T, Yun F, Zhong J*. Food and gut originated bacteriocins involved in gut microbe-host interactions. Critical Reviews in Microbiology 2023 Aug;49(4):515-527.
8. Huang F#, Wang T#, Zhang J, Tahir M, Sun J, Liu Y, Yun F, Xia T, Teng K, Wang J, Zhong J*. Exploring the bacterial community succession and metabolic profiles of Lonicera japonica Thunb. residues during anaerobic fermentation. Bioresource Technology 2022. Jan; 367:128264.
9. Gu S#, Zhang J#, Li L, Zhong J*. Repurposing the endogenous CRISPR-Cas9 system for high-efficiency genome editing in Lacticaseibacillus paracasei. ACS Synthetic Biology 2022 Dec 16;11(12):4031-4042.
10. Wang T, Zhang J, Shi W, Sun J, Xia T, Huang F, Liu Y, Li H, Teng K, Zhong J*. Dynamic changes in fermentation quality and structure and function of the microbiome during mixed silage of Sesbania cannabina and sweet sorghum grown on saline-alkaline land. Microbiology Spectrum. 2022 Oct 26;10(5):e0248322.
11. Zhang J, Li L, Zhang T, Zhong J*. Characterization of a novel type of glycogen-degrading amylopullulanase from Lactobacillus crispatus. Applied Microbiology and Biotechnology, 2022. Jun;106(11):4053-4064
12. Zhang J#, Li L#, Gu S, Teng K, Ren J, Liu G, Zhong J*. Characterization of a novel fructosyltransferase InuCA from Lactobacillus crispatus that attaches to the cell surface by electrostatic interaction. Applied and Environmental Microbiology. 2022 Feb 22;88(4):e0239921.
13. Huang F, Teng K, Liu Y, Wang T, Xia T, Yun F, Zhong J*. Nisin Z attenuates lipopolysaccharide-induced mastitis by inhibiting the ERK1/2 and p38 mitogen-activated protein kinase signaling pathways. Journal of Dairy Science. 2022 Apr;105(4):3530-3543.
14. Liu Y#, Teng K#, Huang F, Xia T, Zhang J, Wang T, Zhong J*. High-throughput discovery of novel lanthipeptides and producers by metagenomic mining of isolates population (MMIP) from Chinese spicy cabbage. Food research International. 2022 April 154,110991.
15. Huang F#, Teng K#, Liu Y, Cao Y, Wang T, Ma C, Zhang J, Zhong J*. Bacteriocins: Potential for Human Health. Oxiditive Medicine and Cellular Longevity. 2021 Apr 10;2021:5518825.
16. Wang T, Teng K, Cao Y, Shi W, Xuan Z, Zhou J, Zhang J, Zhong J*. Effects of Lactobacillus hilgardii 60TS-2, with or without homofermentative Lactobacillus plantarum B90, on the aerobic stability, fermentation quality and microbial community dynamics in sugarcane top silage. Bioresource Technology 2020 (312) 123600.
17. Yang X#, Teng K#, Li L, Su R, Zhang J, Ai G, Zhong J*. Transcriptional regulator AcrR increases ethanol tolerance through regulation of fatty acid synthesis in Lactobacillus plantarum. Applied and Environmental Microbiology. 2019 Oct 30;85(22).
18. Yang X#, Teng K#, Su R, Li L, Zhang T, Fan K, Zhang J, Zhong J*. AcrR and Rex control mannitol and sorbitol utilization through their cross-regulation of aldehyde-alcohol dehydrogenase (AdhE) in Lactobacillus plantarum. Applied and Environmental Microbiology 2019 Feb 6;85(4). pii: e02035-18.
19. Zhang L, Teng K, Wang J, Zhang Z, Zhang J, Sun S, Li L, Yang X, Zhong J*. CerR, a single-domain regulatory protein of the LuxR family, promotes cerecidin production and immunity in Bacillus cereus. Applied and Environmental Microbiology 2018 Feb 14; 84(5).
20. Ni K, Zhao J, Zhu B, Su R, Pan Y, Ma J, Zhou G, Tao Y, Liu X, Zhong J*. Assessing the fermentation quality and microbial community of the mixed silage of forage soybean with crop corn or sorghum. Bioresource Technology 2018 Oct; 265:563-567.
21. Ni K, Wang F, Zhu B, Yang J, Zhou G, Pan Y, Tao Y, Zhong J*. Effects of lactic acid bacteria and molasses additives on the microbial community and fermentation quality of soybean silage. Bioresource Technology. 2017 Apr 20;238:706-715.
22. Ge X, Teng K*, Wang J, Zhao F, Wang F, Zhang J, Zhong J*. Ligand determinants of nisin for its induction activity. Journal of Dairy Science. 2016 Jul; 99(7):5022-31.
23. Teng K, Zhang J, Zhang X, Ge X, Gao Y, Wang J, Lin Y, Zhong J*. Identification of ligand specificity determinants in lantibiotic bovicin HJ50 and the receptor BovK, a Multi-transmembrane histidine kinase. Journal of Biological Chemistry 2014 289:9823-9832.
24. Zhang J, Feng Y, Teng K, Lin Y, Gao Y, Wang J, Zhong J*. Type AII lantibiotic bovicin HJ50 with a rare disulfide bond: structure, structure-activity relationships and mode of action. Biochemical Journal 2014 461: 497-508.
25. Wang J, Zhang Li, Teng K, Sun S, Sun Z, Zhong J*. Cerecidins, novel lantibiotics from Bacillus cereus with potent antimicrobial activity. Applied and Environmental Microbiology 2014 80(8): 2633-2643.
26. Wang J, Gao Y, Teng K, Zhang J, Sun S, Zhong J*. Restoration of a bioactive lantibiotic suicin from a remnant lan locus of pathogenic Streptococcus suis serotype. Applied and Environmental Microbiology 2014 80(3): 1062-1071.
27. Gao Y, Lu Y, Teng K, Chen M, Zheng H, Zhu Y, Zhong J*. Complete genome sequence of Lactococcus lactis subsp. lactis CV56, a probiotic strain isolated from the vagina of healthy women. Journal of Bacteriology 2011 193(11): 2886-2887.  
28. Lin Y, Teng K, Huan L, Zhong J *. Dissection of the bridging pattern of bovicin HJ50, a lantibiotic containing a characteristic disulfide bridge. Microbiological Research 2011 166: 146-154.
29. Zhang Q, Zhong J*, Huan L*. Expression of Hepatitis B Virus surface antigen determinants in Lactococcus lactis for oral vaccination. Microbiological Research 2011 166: 111-120.
30. Liang X, Sun Z, Zhong J*, Zhang Q, Huan L*. Adverse effect of nisin resistance protein on nisin-induced expression system in Lactococcus lactis. Microbiological Research 2010 165: 458-465.
31. Sun Z, Zhong J*, Liang X, Liu J, Chen X, and Huan L *. Novel mechanism for nisin resistance via proteolytic degradation of nisin by nisin resistance protein (NSR). Antimicrobial Agents and Chemotherapy 2009 53:1964-1973.

Awarded the National Women's Pacesetter in 2021
Selected as the CAS Person of the Year in 2020