Plant Virology and Plant Biotechnology

EDUCATION EXPERIENCE
1962-1967 Department of Chemistry, Fudan University
PROFESSIONAL EXPERIENCE
1968-1978 Research Assistant, Institute of Microbiology, Chinese Academy of Sciences
1978-1986 Research Associate, Institute of Microbiology, Chinese Academy of Sciences
1986-1990 Associate Research Fellow, Institute of Microbiology, Chinese Academy of Sciences
1990- Research Fellow, Institute of Microbiology, Chinese Academy of Sciences
1992-1999 Deputy Director, Institute of Microbiology, Chinese Academy of Sciences
2000-2004 Director, Institute of Microbiology, Chinese Academy of Sciences
1991-2001 Deputy Director, CAS Key Laboratory of Plant Biotechnology
2001-2003 Director, CAS Key Laboratory of Plant Biotechnology
2004-2011 Director, State Key Laboratory of Plant Genomics
2006-2010 Director, College of Agriculture and Biotechnology, Zhejiang University
2006-2011 Visiting Professor, Centre for Plant Sciences, University of Leeds
INTERNATIONAL EXPERIENCES
1979-1981 Visiting Scholar in Laboratory of Molecular Biology, State University of Ghent, Belgium
1985-1988 Visiting Scientist in Laboratory of Plant Molecular Biology, The Rockefeller University, USA
1989-1995 Rockefeller Foundation Biotechnology Career Fellowship

1. Fang, R.; Min Jou, W.; Huylebroeck, D.; Devos, R.; Fiers, W. Complete Structure of A/Duck/Ukraine/63 Influenza Hemagglutinin Gene: Animal Virus as Progenitor of Human H3 Hong Kong 1968 Influenza Hemagglutinin. Cell 1981, 25 (2), 315–323. https://doi.org/10.1016/0092-8674(81)90049-0.
2. 方荣祥; 吴晓军; 卜明; 田颖川; 蔡发兴; 莽克强. 花椰菜花叶病毒(新疆分离物)基因组DNA的全部核苷酸序列. 病毒学报 1985, 1 (03), 247–256.
3. Fang, R. X.; Nagy, F.; Sivasubramaniam, S.; Chua, N. H. Multiple Cis Regulatory Elements for Maximal Expression of the Cauliflower Mosaic Virus 35S Promoter in Transgenic Plants. The Plant cell 1989, 1 (1), 141–150. https://doi.org/10.1105/tpc.1.1.141.
4. 方荣祥; 田颖川; 王桂玲; 秦晓峰; 杨毛周; 李太元; 许丙寅; 莽克强; 张振臣; 吴青; 周汝鸿; 王凤龙; 赵钢; 韩晓东. 抗烟草和黄瓜花叶病毒的双价抗病毒工程烟草. 科学通报 1990, 35 (17), 1358–1359. https://doi.org/10.1360/csb1990-35-17-1358-x.
5. 方荣祥; 田颖川; 王桂玲; 许丙寅; 李太元; 莽克强; 张振臣; 吴青; 周汝鸿; 王凤龙; 史万华; 韩晓东. 双抗转基因烟草纯合系的选育及田间试验. 中国科学(B辑) 1993, 23 (05), 481–488.
6. Fang, R. X.; Wang, Q.; Xu, B. Y.; Pang, Z.; Zhu, H. T.; Mang, K. Q.; Gao, D. M.; Qin, W. S.; Chua, N. H. Structure of the Nucleocapsid Protein Gene of Rice Yellow Stunt Rhabdovirus. Virology 1994, 204 (1), 367–375. https://doi.org/10.1006/viro.1994.1541.
7. Cai, W. Q.; Fang, R. X.; Shang, H. S.; Wang, X.; Zhang, F. L.; Li, Y. R.; Zhang, J. C.; Cheng, X. Y.; Wang, G. L.; Mang, K. Q. Development of CMV-and TMV-Resistant Chili Pepper: Field Perfermance and Biosafety Assessment. Molecular Breeding 2003, 11 (1), 25–35. https://doi.org/10.1023/A:1022655204552.
8. Huang, Y.; Zhao, H.; Luo, Z.; Chen, X.; Fang, R. X. Novel Structure of the Genome of Rice Yellow Stunt Virus: Identification of the Gene 6-Encoded Virion Protein. J Gen Virol 2003, 84 (Pt 8), 2259–2264.
9. Jia, H. G.; Pang, Y. Q.; Fang, R. X. Agroinoculation as a Simple Way to Deliver a Tobacco Mosaic Virus-Based Expression Vector. Acta Botanica Sinica 2003, 45 (07), 770–773.
10. Liu, Z. Z.; Wang, J. L.; Huang, X.; Xu, W. H.; Liu, Z. M.; Fang, R. X. The Promoter of a Rice Glycine-Rich Protein Gene, Osgrp-2, Confers Vascular-Specific Expression in Transgenic Plants. Planta 2003, 216 (5), 824–833. https://doi.org/10.1007/s00425-002-0934-y.
11. Huang, Y. W.; Geng, Y. F.; Ying, X. B.; Chen, X. Y.; Fang, R. X. Identification of a Movement Protein of Rice Yellow Stunt Rhabdovirus. J Virol 2005, 79 (4), 2108–2114. https://doi.org/10.1128/jvi.79.4.2108-2114.2005.
12. Li, Y.; Wang, L.; Li, S.; Chen, X.; Shen, Y.; Zhang, Z.; He, H.; Xu, W.; Shu, Y.; Liang, G.; Fang, R.; Hao, X. Seco-Pregnane Steroids Target the Subgenomic RNA of Alphavirus-like RNA Viruses. Proc Natl Acad Sci U S A 2007, 104 (19), 8083–8088. https://doi.org/10.1073/pnas.0702398104.
13. Qu, J.; Ye, J.; Fang, R. Artificial microRNA-Mediated Virus Resistance in Plants. J Virol 2007, 81 (12), 6690–6699. https://doi.org/10.1128/jvi.02457-06.
14. Zhang, L.; Jia, Y.; Wang, L.; Fang, R. A Proline Iminopeptidase Gene Upregulated in Planta by a LuxR Homologue Is Essential for Pathogenicity of Xanthomonas Campestris Pv. Campestris. Mol Microbiol 2007, 65 (1), 121–136. https://doi.org/10.1111/j.1365-2958.2007.05775.x.
15. Wang, L.; Zhang, L.; Geng, Y.; Xi, W.; Fang, R.; Jia, Y. XerR, a Negative Regulator of XccR in Xanthomonas Campestris Pv. Campestris, Relieves Its Repressor Function in Planta. Cell Res 2011, 21 (7), 1131–1142. https://doi.org/10.1038/cr.2011.64.
16. Hamera, S.; Song, X.; Su, L.; Chen, X.; Fang, R. Cucumber Mosaic Virus Suppressor 2b Binds to AGO4-Related Small RNAs and Impairs AGO4 Activities. Plant J 2012, 69 (1), 104–115. https://doi.org/10.1111/j.1365-313X.2011.04774.x.
17. Guo, H.; Song, X.; Xie, C.; Huo, Y.; Zhang, F.; Chen, X.; Geng, Y.; Fang, R. Rice Yellow Stunt Rhabdovirus Protein 6 Suppresses Systemic RNA Silencing by Blocking RDR6-Mediated Secondary siRNA Synthesis. Mol Plant Microbe Interact 2013, 26 (8), 927–936. https://doi.org/10.1094/mpmi-02-13-0040-r.
18. Zhang, Y.; Zhang, G.; Xiao, N.; Wang, L.; Fu, Y.; Sun, Z.; Fang, R.; Chen, X. The Rice “nutrition Response and Root Growth” (NRR) Gene Regulates Heading Date. Mol Plant 2013, 6 (2), 585–588. https://doi.org/10.1093/mp/sss157.
19. Huo, Y.; Liu, W.; Zhang, F.; Chen, X.; Li, L.; Liu, Q.; Zhou, Y.; Wei, T.; Fang, R.; Wang, X. Transovarial Transmission of a Plant Virus Is Mediated by Vitellogenin of Its Insect Vector. PLoS Pathog 2014, 10 (3), e1003949. https://doi.org/10.1371/journal.ppat.1003949.
20. Zhang, G.; Song, X.; Guo, H.; Wu, Y.; Chen, X.; Fang, R. A Small G Protein as a Novel Component of the Rice Brassinosteroid Signal Transduction. Mol Plant 2016, 9 (9), 1260–1271. https://doi.org/10.1016/j.molp.2016.06.010.
21. Xie, C. M.; Zhang, G.; An, L.; Chen, X. Y.; Fang, R. X. Phytochrome-Interacting Factor-like Protein OsPIL15 Integrates Light and Gravitropism to Regulate Tiller Angle in Rice. Planta 2019, 250 (1), 105–114. https://doi.org/10.1007/s00425-019-03149-8.
22. Huang, W.; Zhang, Y.; Xiao, N.; Zhao, W.; Shi, Y.; Fang, R. Trans ‐complementation of the Viral Movement Protein Mediates Efficient Expression of Large Target Genes via a Tobacco Mosaic Virus Vector. Plant Biotechnology Journal 2024, 22 (11), 2957–2970. https://doi.org/10.1111/pbi.14418.

AWARDS
1987 Two Science and Technology Advancement Prizes second-class awarded by Chiense Academy of Sciences
1990 One Science and Technology Advancement Prize second-class awarded by Chiense Academy of Sciences
1991 One Science and Technology Advancement Prize first-class awarded by Chiense Academy of Sciences
1993 One Science and Technology Advancement Prize first-class awarded by Henan Province
1993 One Science and Technology Advancement Prize first-class awarded by Chiense Academy of Sciences
1994 One Young and Middle-aged expert with Outstanding Contributions titled by Ministry of Personnel
2005 Science and Technology Advancement Prize awarded by The Holeung Ho Lee Foundation
2016 Lifetime Achievement Award from the Chinese Phytopathological Society
HONORS
1994  Outstanding Middle-aged and Young Experts titled by the Ministry of Human Resources and Social Security
2003 Academician, Chinese Academy of Sciences
2007 Fellow, Academy of Sciences for the Developing World