1.Gangming Xu#, Juan Wang#, Linqi Wang, Xiuyun Tian, Haihua Yang, Keqiang Fan, Keqian Yang*, and Huarong Tan*. 2010. 'Pseudo' gamma-butyrolactone receptors respond to antibiotic signals to coordinate antibiotics biosynthesis. Journal of Biological Chemistry (online) doi:10.1074/jbc.M110.143081 (# shared the first author) (IF 5.328)

2.Haihua Yang, Yang An, Linqi Wang, Shuli Zhang, Yue Zhang, Yuqing Tian, Gang Liu, Huarong Tan*. 2010. Autoregulation of hpdR and its effect on CDA biosynthesis in Streptomyces coelicolor. Microbiology-SGM. [Epub ahead of print] (IF 3.025)

3.Guohua Zhang, Yuqing Tian, Kun Hu, Chi Feng and Huarong Tan*. 2010. SCO3900, co-transcripted with three downstream genes, is involved in the differentiation of Streptomyces coelicolor. Current Microbiology. 60(4): 268-273 (IF 1.330)

4.Xihong He, Rui Li, Yuanyuan Pan, Gang Liu* and Huarong Tan*. 2010. SanG, a transcriptional activator, controls nikkomycin biosynthesis through binding to the sanN-sanO intergenic region in Streptomyces ansochromogenes.  Microbioogy-SGM. 156:828 (IF 2.841)

5.Guojian Liao, Jin’e Li, Lei Li, Haihua Yang, Yuqing Tian, Huarong Tan*. 2010. Cloning, reassembling and integration of the entire nikkomycin biosynthetic gene cluster into Streptomyces ansochromogenes lead to an improved nikkomycin production. Microbial Cell Factories. 9:6, doi:10.1186/1475- 2859-9-6 (IF 3.338)

6.Rui Li, Gang Liu, Zhoujie Xie, Xihong He, Wenqing Chen, Zixin  Deng and Huarong Tan*. 2010. PolY, a transcriptional regulator with ATPase activity, directly activates transcription of polR in polyoxin biosynthesis in Streptomyces cacaoi. Molecular Microbiology. 75(2): 349-364. (IF 5.213)

7.Shuli Zhang#, Bo Liu#, Haihua Yang*, Yuqing Tian, Gang Liu, Lei Li and Huarong Tan*. 2010. Characterization of EndoTT, a novel single-stranded DNA specific endonuclease from Thermoanaerobacter tengcongensis. Nucleic Acids Research. (accepted). (IF 6.878)

8.Guojian Liao, Jin’e Li, Lei Li, Haihua Yang, Yuqing Tian and Huarong Tan*. 2009. Selectively improving nikkomycin Z production by blocking the imidazolone biosynthetic pathway of nikkomycin X and uracil feeding in Streptomyces ansochromogenes. Microbial Cell Factories. 8:61, doi:10.1186/1475-2859-8-61. (IF 3.338)

9.Rui Li#, Zhoujie Xie#, Yuqing Tian, Haihua Yang, Wenqing Chen, Delin You, Gang Liu, Zixin Deng*, and Huarong Tan*. (2009). polR, a pathway-specific transcriptional regulatory gene, positively controls polyoxin biosynthesis in Streptomyces cacaoi var. Asoensis. Microbiology-SGM 155:1819-1831 (IF 2.841)

10.Yuanyuan Pan#, Gang Liu#, Haihua Yang, Yuqing Tian and Huarong Tan*. (2009). The pleiotropic regulator AdpA-L directly controls the pathway-specific activator of nikkomycin biosynthesis in Streptomyces ansochromogenes. Molecular Microbiology (#shared the first author) 72(3): 710-723. (IF 5.462)

11.Linqi Wang#, Xiuyun Tian#, Juan Wang, Haihua Yang, Keqiang Fan, Gangming Xu, Keqian Yang*, and Huarong Tan*. (2009). Autoregulation of antibiotic biosynthesis: direct binding of jadomycin to an atypical response regulator. Proceedings of the National Academy of Sciences of the United States of America (#shared the first author) 106(21): 8617-8622. (IF 9.598)

12.Wenqing Chen, Tingting Huang, Xinyi He, Qingqing Meng, Delin You, Linquan Bai, Jialiang Li, Mingxuan Wu, Rui li, Zhoujie Xie, Huchen Zhou, Xiufen Zhou, Huarong Tan*, and Zixin Deng*. (2009).Characterization of the polyoxin biosynthetic gene cluster from Streptomyces cacaoi and engineered production of polyoxin H. The Journal of Biological Chemistry 284(16): 10627-10638 (IF 5.581)

13.Yanhua LiJihui Zhang , Huarong Tan*.2008. Identification of a Nitroalkane oxidase gene: naoA related to the growth of Streptomyces ansochromogenes.Current Microbiology 57: 588-592. (IF 1.167)

14.Hongbo Ling, Guojun Wang, Jin’e Li, Huarong Tan*. 2008. sanN encoding a dehydrogenase is essential for nikkomycin biosynthesis in Streptomyces ansochromogenes. Journal of Microbiology and Biotechnology 18(3):397-403. PDF (IF 2.062)

15.Yue Zhang, Linqi Wang, Shuli Zhang, Haihua Yang* and Huarong Tan. hmgA, transcriptionally activated by HpdA, influences the biosynthesis of actinorhodin in Streptomyces coelicolor. FEMS Microbiology Letters 280:219-225.2008. PDF (IF 2.274)

16.Liang Liang, Xihong He, Gang Liu* and Huarong Tan*. The role of a purine-specific nucleoside hydrolase in spore germination of Bacillus thuringiensis. Microbiology-SGM 154:1333-1340. 2008. PDF (IF 3.110)

17.Haihua Yang, Linqi Wang, Zhoujie Xie, Yuqing Tian, Gang Liu, Huarong Tan*. The tyrosine degradation gene hppD is transcriptionally activated by HpdA and repressed by HpdR in Streptomyces coelicolor, while hpdA is negatively autoregulated and repressed by HpdR. Molecular Microbiology. 65 : 1064-1077, 2007.

18.Yuqing Tian, Kay Fowler, Kim Findlay, Huarong Tan* & Keith F. Chater*. An unusual response regulator influences sporulation at early and late stages in Streptomyces coelicolor. Journal of Bacteriology. 189 : 2873-2885, 2007.

19.Hongbo Ling, Guojun Wang, Yuqing Tian, Gang Liu and Huarong Tan*. SanM catalyzes the formation of 4-pyridyl-2-oxo-4-hydroxyiso- valerate in nikkomycin biosynthesis by interacting with SanN. Biochemical and Biophysical Research Communications. 361: 196-201, 2007.

20.Jia Lianghui , TianYuqing, Tan Huarong*. SanT, a bidomain protein, is essential for nikkomycin biosynthesis of S. an sochromogenes. Biochemical and Biophysical Research Communications. 362: 1031-1036, 2007.

21.Zhoujie Xie, Wenli Li, Yuqing Tian, Gang Liu & Huarong Tan*. Identification and characterization of sawC, a whiA-like gene, essential for sporulation in Streptomyces ansochromogenes. Archives of Microbiology. 188: 575-582, 2007

Patent

谭华荣 刘 钢 尼可霉素生物合成调控基因及其编码蛋白与表达工程菌. 2007. 授权号: ZL 2004 1 0058411.2.