Protein translation is the final step of the central dogma of biology, and regulation at this step can immediately change protein levels and allows for a rapid response to physiological changes, such as plant immune responses to pathogen infection. After all, proteins execute most of biological functions in cells. However, due to the intrinsic complexity of the translational process and technical limitations, our knowledge of how translation is regulated in plants upon pathogen challenge is still rudimentary. Our lab focuses on elucidating the immune signaling and translational regulations during host-microbe interaction, aiming to provide new targets/techniques for controlling pathogens, breeding disease-resistant crops, and producing biomacromolecules through plant-based reactors.

Ph.D. 2012-2017 

Genetics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China

M.S. 2009-2012 

Crop Genetics and Breeding, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing, China

B.S. 2005-2009 

Agronomy (Tobacco), Qingdao Agricultural University, Shandong, China

2023.06-Present

Principle Investigator, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China

2023.01 - 2023.06 

Research Scientist, Duke University, Durham, USA

2017.12 - 2022.11 

Research Associate, Duke University, Durham, USA

1. Ma, M., Li, M., Zhou, R., Yu, J., Wu, Y., Zhang, X., Wang, J., Zhou, J*., Liang, X*. (2023). CPR5 positively regulates pattern-triggered immunity via a mediator protein, J. Integr. Plant Biol., 00(00): 1-7.
2. Wang, J., Zhang, X., Greene, G. H., Xu, G., and Dong, X. (2022). PABP/purine-rich motif as an initiation module for cap-independent translation in pattern-triggered immunity. Cell, 185(17): 3186-3200.
3. Wang, X., Ding, Y., Li, Z., Shi, Y., Wang, J., Hua, J., Gong, Z., Zhou, J. M., Yang, S. (2019). PUB25 and PUB26 Promote Plant Freezing Tolerance by Degrading the Cold Signaling Negative Regulator MYB15. Dev. Cell, 2019, 51(2): 222-235.
4. Zhang, D., Wang, J., Wang, D., Kong, Z., Zhou, L., Zhang, G., Gui, Y., Li, J., Huang, J., Wang, B., Liu, C., Yin, C., Li, R., Li, T., Wang, J., Short, D., Klosterman, S., Bostock, R., Dai, X. (2019). Population genomics demystifies the defoliation Verticillium dahliae, New Phytol., 222(2): 1012-1029.
5. Wang, J., Grubb, L., Wang, J., Liang, X., Li, L., Gao, C., Ma, M., Feng, F., Li, M., Li, L., Zhang, X., Yu, F., Xie, Q., Chen, S., Zipfel, C., Monaghan, J., and Zhou, J. (2018). A regulatory module controlling homeostasis of a plant immune kinase. Mol. Cell, 2018, 69(3): 493-504.
6. Liang, X., Ma, M., Zhou, Z., Wang, J., Yang, X., Rao, S., Bi, G., Li, L., Zhang, X., Chai, J., Chen, S., Zhou, J. (2018). Ligand-triggered de-repression of Arabidopsis heterotrimeric G proteins coupled to immune receptor kinases. Cell Res., 2018, 28(5): 529-543.
7. Qi, J#., Wang, J#., Gong, Z*., and Zhou, J.M*. (2017). Apoplastic ROS signaling in plant immunity. Curr. Opin. Plant Biol. 38, 92-100.
8. Liang, X., Ding, P., Lian, K., Wang, J., Ma, M., Li, L., Li, M., Zhang, X., Chen, S., Zhang, Y., et al. (2016). Arabidopsis heterotrimeric G proteins regulate immunity by directly coupling to the FLS2 receptor. eLife 5, e13568.
9. Wu, J., Sun Y, Zhao, Y., Zhang, J., Luo, L., Li, M., Wang, J., Yu, H., Liu, G., Yang, L., et al. (2015). Deficient plastidic fatty acid synthesis triggers cell death by modulating mitochondrial reactive oxygen species. Cell Res. 25, 621-633.
10. Chen, J., Huang, J., Li, N., Ma, X., Wang, J., Liu, C., Liu, Y., Liang, Y., Bao, Y., and Dai, X. (2015). Genome-wide analysis of the gene families of resistance gene analogues in cotton and their response to Verticillium wilt. BMC plant biol. 15, 148.
11. Liu, S., Chen, J., Wang, J., Li, L., Xiao, H., Adam, S., and Dai, X. (2013). Molecular characterization and functional analysis of a specific secreted protein from highly virulent defoliating Verticillium dahliae. Gene 529, 307-316.