The increasing atmospheric carbon dioxide concentration is one of the major contributors to anthropogenic climate change, which has aroused great concern worldwide. In nature, plants and microbes fix carbon dioxide through carbon fixation pathways. Two synthetic carbon fixation pathways, the CETCH cycle and the ASAP pathway, have also been reported in recent years. However, these pathways usually contain multiple (more than 10) reactions. IMCAS researchers designed and experimentally demonstrated a minimized synthetic carbon fixation cycle which only contains four enzymatic reactions but shows a higher efficiency than that of the CETCH cycle.