Principal Investigator,Professor :
1.Xiao Y, Zhang W, Pan M, Bauer DLV, Bi Y, Cao M, Fodor E, Deng T. A synergistic effect between 3' terminal noncoding and adjacent coding regions of influenza A virus HA segment on template preference. J. Virol. 2021 Jun doi: 10.1128/JVI.00878-21.
2.Gao S, Zhang W, Lu C, Cao M, Cen S, Peng Y, Deng T. Identification of a Type-Specific Promoter Element That Differentiates between Influenza A and B Viruses. J. Virol. 2019 Nov 13;93(23):e01164-19. doi: 10.1128/JVI.01164-19
3.Wang J, Li J, Zhao L, Cao M, Deng T. Dual Roles of the Hemagglutinin Segment-Specific Noncoding Nucleotides in the Extended Duplex Region of the Influenza A Virus RNA Promoter. J Virol. 2017, 91(1), e01931-16.
4.Wang J, Peng Y, Zhao L, Cao M, Hung T, Deng T. Influenza A virus Utilizes a Suboptimal Kozak Sequence to Fine-tune Virus Replication and Host Response. J Gen Virol. 2014 Dec 17. doi: 10.1099/vir.0.00003
5.Li C, Wu A, Peng Y, Wang J, Guo Y, Chen Z, Zhang H, Wang Y, Dong J, Wang L, Qin FX, Cheng G, Deng T*, Jiang T*. Integrating computational modeling and functional assays to decipher the structure-function relationship of influenza virus PB1 protein. Sci Rep. 2014, 26;4:7192. doi: 10.1038/srep07192. (*co-corresponding authors).
6.Cao M, Wei C, Zhao L, Wang J, Jia Q, Wang X, Jin Q, Deng T. DnaJA1/Hsp40 is co-opted by influenza A virus to enhance its viral RNA polymerase activity. J Virol. 2014, 88(24): 14078-14089.
7.Zhao L, Peng Y, Zhou K, Cao M, Wang J, Wang X, Jiang T, Deng T. New Insights into the Nonconserved Noncoding Region of the Subtype-Determinant Hemagglutinin and Neuraminidase Segments of In?uenza A Viruses. J Virol. 2014, 88(19): 11493-11503.
8.Zhou Z, Cao M, Guo Y, Zhao L, Wang J, Jia X, Li J, Wang C, Gabriel G, Xue Q, Yi Y, Cui S, Jin Q*, Wang J*, Deng T*. Fragile X mental retardation protein stimulates ribonucleoprotein assembly of Influenza A virus. Nat Commun. 2014,5:3259.
9.Li C, Ba Q, Wu A, Zhang H, Deng T*, Jiang T*. A peptide derived from C-terminus of PB1 inhibits influenza virus replication by interfering with viral polymerase assembly. FEBS J. 2012 280(4):1139-49. (*co-corresponding authors).
10.Dreger M, Leung BW, Brownlee GG*, Deng T*. A quantitative proteomics strategy to detect protein regions affected by protein-protein interactions. Protein Science 2009, 18(7):1448-58..
11.Chase G*, Deng T*, Fodor E, Mayer D, Schwemmle M and Brownlee GG (2008), Hsp90 inhibitors reduce influenza virus replication in cell culture. Virology 2006 377(2):431-439 (* co-first authors).
12.Fodor E, Engelhardt OG, Smith M, Sharps J, Brownlee GG, Deng T* (2007). Nuclear import and assembly of the influenza virus RNA polymerase complex. In “Options for the Control of Influenza VI” 2007, Elsevier Science, Toronto, Canada.
13.Deng T*, Engelhardt OG*, Thomas B, Akoulitchev AV, Brownlee GG and Fodor E. The role of Ran binding protein 5 (RabBP5) in the nuclear import and assembly of he influenza virus RNA polymerase complex. J Virol. 2006 80:11911-11919.
14.Deng T, Sharps J, Brownlee GG. The role of the influenza virus heterotrimeric RNA polymerase complex in the initiation of replication. J Gen.Virol. 2006, 87: 3373-3377.
15.Deng T*, Vreede FT*, Brownlee GG. Different de novo initiation strategies are used by influenza virus RNA polymerase on its cRNA and viral RNA promoters during viral RNA replication. J Virol. 2006, 80:2337-2348..
16.Deng T, Sharps J, Fodor E, Brownlee GG. In vitro assembly of PB2 with PB1-PA dimer supports a new model assembly of influenza A virus polymerase subunits into a functional trimeric complex. J Virol. 2005, 79:8669-8674
17.Crow M*, Deng T*, Addley M, Brownlee GG. Mutational analysis of the influenza virus cRNA promoter and identification of nucleotides critical for replication. J Virol. 2004, 78:6263-6270. (* co-first authors)