Principal Investigator,Professor : Group of Extremophiles and Industrial Synthetic Biotechnology

YU Bo(Director)
Title:Associate Professor, Ph.D
Dept.:CAS Key Laboratory of Microbial Physiological and Metabolic Engineering
Address:NO.1 Beichen West Road, Chaoyang District, Beijing 100101, P. R. China
Post-Doc. (Humboldtian) 2008-2010. German Research Centre for Biotechnology and Hamburg University of Technology, Germany
Ph.D. in Microbiology. June 2006. Shandong University, Jinan, China.
B.S. in Biotechnology. June 2001. Shandong University, Jinan, China.
Research Interests
Organisms from extreme environments represent an expanding pool of untapped biocatalytic capacity. Extremophiles could thrive under extremes of temperature, pH, salinity, or some combination of otherwise ‘abiotic’ conditions which are very similar with the real industrial production conditions. The challenging environments of extremophiles highlight their great potential for industrial biotechnology. Our group focuses on the synthetic biotechnology for important bio-based chemicals production by using extremophiles as producers:
-Screening, engineering and application of extremophiles with industrial potentials
-Synthetic biotechnology for bio-based platform and high value-added fine chemicals production and their industrialization
[1] Peng LL, Wang LM, Che CC, Yang G, Yu B*, Ma YH. Bacillus sp. strain P38: an efficient producer of L-lactate from cellulosic hydrolysate, with high tolerance for 2-furfural. Bioresour. Technol. 2013, 149: 169-176.
[2] Jiang X, Xue YF, Wang LM, Yu B*, Ma YH. Genome sequence of a novel polymer-grade L-lactate-producing alkaliphile, Exiguobacterium sp. strain 8-11-1. Genome Announcements 2013; 1(4).
[3] Yu D, Jiang YJ, Hou JF, Chen S, Zhang GF, Liu X, Dong H*, Yu B*. Crystallization and preliminary X-ray study of the deaminase AmnE from Pseudomonas sp. AP-3. Acta Cryst. 2013, F69: 812-814.
[4] Jiang X, Xue YF, Wang AY, Wang LM, Zhang GM, Zeng QT, Yu B*, Ma YH. Efficient production of polymer-grade L-lactate by an alkaliphilic Exiguobacterium sp. strain under nonsterile open fermentation conditions. Bioresour. Technol. 2013, 143: 665-668.
[5] Li Y, Wang LM, Ju JS, Yu B*, Ma YH. Efficient production of polymer-grade D-lactate by Sporolactobacillus laevolacticus DSM442 with agricultural waste cottonseed as the sole nitrogen source. Bioresour. Technol. 2013, 142: 186-191.
[6] Wang LM, Xue ZW, Zhao B, Yu B*, Xu P, Ma YH. Jerusalem artichoke powder: A useful material in producing high-optical-purity L-lactate using an efficient sugar-utilizing thermophilic Bacillus coagulans strain. Bioresour. Technol. 2013, 130: 174-180.
[7] Yu B*, Zeng Y, Jiang X, Wang LM, Ma YH. Trends in polymer-grade L-lactic acid fermentation by non-food biomass. Chin. J. Biotech. 2013, 29(4): 411-421. (Editor invited review article)
[8] Jiang X, Wang LM, Zhang GM, Yu B*, Zeng QT*. Recent developments in L-lactate fermentation by genetically modified microorganisms. Chin. J. Biotech. 2013, 29(10): 1-13.
[9] Yu B*, Su F, Wang LM, Zhao B, Qin JY, Ma CQ, Xu P* and Ma YH. Genome sequence of Lactobacillus rhamnosus strain CASL, an efficient L-lactic-acid producer from cheap substrate cassava. J. Bacteriol. 2011, 193: 7013-7014.
[10] Yu B*, Su F, Wang LM, Xu K, Zhao B, and Xu P*. Draft genome sequence of Sporolactobacillus inulinus strain CASD, an efficient D-lactic-acid-producing bacterium with high concentration lactate tolerance capability. J. Bacteriol. 2011, 193: 5864-5865.